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Break the ground “loop” by using a DI box.That way they share the same ground and avoid creating a “loop” between two grounded outlets that might have different voltages.
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Set up a power strip and run power to all devices from it. There are a couple of common solutions to this issue: This will likely result in a noticeable, lovely, 60Hz hum. If someone wants to record the line output of the guitar amp, that will mean directly connecting the amp and the interface, and thereby creating a new connection between those two wall outlets, with their slightly different voltages. This voltage difference is small but important. Even though they’re wired to a single breaker box, sharing a common ground, the voltages at those two outlets will be slightly different from one another (say, 115V vs. Let’s say that an amp and an audio interface in a studio are plugged into different electrical outlets on different walls. Your guitar cables will also have shielding to carry interference to the ground. The AC lead from the amp, the extension cable, the power strip, and the outlet should all be three-pronged. An electrical amplifier chain should be grounded. Without going into a bunch of incomprehensible electrical babble, here’s the skinny. What if your amp is buzzing regardless of whether your guitar is plugged in or not? Chances are this finicky problem is a grounding issue or a ground loop. A good option to reach for when recording a quiet, clean part is a Les Paul with dual humbuckers. A single humbucking pickup is essentially two single-coil pickups in one, already canceling out interference. If you have the luxury, use an axe with humbucking pickups.At the cost of changing the tone, it’ll at least taper the electromagnetic interference. On a guitar with two single coil pickups, the neck pickup has the inverse polarity of the bridge pickup, so that middle position (combining the two pickups) cancels out interference. There’s usually a “sweet spot” with the least amount of electrical interference - you’ll hear it when you get there. There are a few simple ways to combat this: Does the hum come back? If so, the hum could be caused by electromagnetic interference from fluorescent lights, dimmers, computer monitors, or other unshielded sources. Plug the guitar back in and turn up the volume knob on the instrument.
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